(Courses are listed in numerical order according to the last two digits)
5301 NEUROSCIENCE / Lectures and laboratory sessions on gross and microscopic anatomy of the human central and peripheral nervous system. Neurophysiology of the central nervous system, peripheral nerves, special sense, autonomics and clinical mediation. Hutchins - 2 sem. hrs.
5402 GENERAL HISTOLOGY / General histology and microscopic anatomy of the four basic tissues. Laboratory study of electron micrographs and computerized images is employed. Opperman - 3 sem. hrs.
5603 GROSS ANATOMY / Conceptual and functional basis for understanding the macroscopic structure of the human body utilizing laboratory dissection of human cadavers. Regional anatomy of the back, thorax, upper limb and head is emphasized. Hutchins - 4 sem. hrs.
5V04 HEAD AND NECK ANATOMY / Special emphasis on surgical anatomy and distribution of nerves and vasculature of particular interest in dentistry. Hutchins - 1.5 sem. hrs.
5205 ORAL HISTOLOGY / Origin and development of the dental tissues and their related structures. Current publications and research reports are used to provide students with an opportunity to investigate some phase of active interest to them and their anticipated future interest in practice. Spears - 3 sem. hrs.
5307 CELLULAR AND MOLECULAR BIOLOGY / Intermediary metabolism of protein, protein synthesis, nucleic acid metabolism and biochemical endocrinology. Faculty -2 sem. hrs.
5208 MICROBIOLOGY / Introduction to basic microbiology with emphasis on oral and medical microbes, taxonomy and microbial physiology. Taught in conjunction with dental curriculum. Additional readings and discussion for graduate students. Honeyman - 3 sem. hrs.
5210 MICROBIOLOGY LABORATORY / Introduction to classical laboratory methods of microbial staining, microscopy, isolation and cultivation. Taught in conjunction with 5208. Honeyman - 1 sem. hr.
5611 MAMMALIAN PHYSIOLOGY / Basic physiological principles of cells, muscle, nerve, blood, heart, circulation, respiration, digestion, excretion, and central nervous system in maintaining homeostasis. Classical laboratory experiments are used to demonstrate these principles. Wong -4 sem. hrs.
5312 APPLIED MEDICAL PHYSIOLOGY / Prerequisite: 5611 or equivalent. Basic physiology of the cardiovascular, respiratory and renal systems. Each area is expanded to include physiology problems seen clinically as they relate to the dental intern. Bellinger - 2 sem. hrs.
5214 CLINICAL PHARMACOLOGY / Selection and evaluation of dentally related drugs and review of current literature; seminar format. Limited to clinical specialty students. Sharma - 1.5 sem. hrs.
5221 RESEARCH DESIGN AND METHODOLOGY / An introduction to the research process; sufficient background in research design and methodology is provided to enable students to critically evaluate literature and assist in the formulation of research projects. Also includes discussion of rules and regulations for human and animal research. Buschang - 2 sem. hrs.
5222 APPLIED BIOSTATISTICS / Overview of applied biostatistics with an emphasis on oral health research. Training includes computer-based instruction in data analysis using SPSS. Schneiderman - 2 sem. hrs.
5324 ADVANCED BIOSTATISTICS / Prerequisites: CS5222 and 5122 or equivalent. Advanced biostatistical methods, including multivariate and longitudinal analysis; computer simulations; applications in craniofacial biology. Buschang - 2 sem. hrs.
5126 RESPONSIBLE CONDUCT IN BIOMEDICAL RESEARCH / Discussion of issues relating to ethical conduct and research. Offered every other year. Dechow - 0.5 sem. hr.
5127 MICROSCOPY, IMAGING, AND ASSOCIATED TECHNIQUES / Principles and methods of microscopy including the usage of scanning electron, light, fluorescent, and confocal microscopes, and computer imaging techniques. Spears - 2 sem. hrs.
5229 THE USE AND CARE OF ANIMALS IN RESEARCH AND TRAINING / Overview of the use and care of laboratory animals. Includes discussion of regulations and ethical issues. Bellinger - 1 sem. hr.
5V40 CELLULAR AND MOLECULAR BIOLOGY OF ORAL AND CRANIOFACIAL TISSUES I / Prerequisites: 5208 or equivalent; 5306 or equivalent. A general survey intended to provide background information concerning the methods and theory of modern cellular/molecular biology. This course lays the groundwork for more advanced study, aids those interested in incorporating cellular/molecular approaches into their research work and enables one to read, understand and evaluate current scientific literature. Qin - 2 sem. hrs. Variable
5341 TECHNIQUES IN CELL AND MOLECULAR BIOLOGY / Principal methods of cellular/molecular investigation of proteins and nucleic acids including immunocytochemistry, western blotting, northern/southern blotting, radioimmunoassay, in situ hybridization, polymerase chain reaction, intracellular recording and fluorescence confocal microscopy. Mues - 1 sem. hr.
5V42 CELLULAR AND MOLECULAR BIOLOGY OF ORAL AND CRANIOFACIAL TISSUES II / Processes of epithelial-mesenchymal interaction as related to odontogenesis, amelogenesis, dentinogenesis, collagen formation, intracellular and extracellular calcium homeostasis, plaque and calculus and wound healing. Opperman - 1 sem. hr. Variable
5243 GENETIC EPIDEMIOLOGY / Introduction to genetic epidemiology and associated study design and data analysis for identifying disease-gene associations. Mitchell and faculty – 2 sem. hrs.
5244 ADVANCED BIOLOGY OF MINERALIZED TISSUES / Overview of the advanced biology of mineralized tissues and their roles in oral health and disease. The course will cover the basic molecular biology of teeth and the skeleton, including bone and cartilage. Other aspects of systemic biology will be explored, such as local and systemic factors that control calcium and phosphate balance, as well as recent advances in molecular biology and research methodologies (molecular biology, gene targeting and histology at both light and electron microscopic levels) for mineralized tissue research. Feng - 2 sem. hrs.
5350 ORAL MICROBIOLOGY / Prerequisites: 5208, 5210 or equivalent. The environment of the mouth is described and its relation to the endogenous and exogenous oral microbiota; relationship between disease and bacterial species; discussion of species differences; molecular mechanisms of bacterial pathogenesis; and host response to oral microbes. Ezzo -3 sem. hrs.
5251 IMMUNOLOGY / Update on the principles of immunology with an emphasis on oral aspects and related diseases. Newman - 2 sem. hrs.
5360 ADVANCED NEUROSCIENCE / Prerequisite: 5301 or equivalent. Advanced concepts of neuroscience are presented with an in-depth coverage of membrane and system function. Hutchins/Wong - 1 sem. hr.
5263 SENSORY NEUROBIOLOGY AND PAIN / An overview of the various sensory systems is explored with the primary emphasis on the processing of pain and temperature information from the craniofacial complex. Hutchins - 1 sem. hr. Odd years
5V69 GROWTH AND MECHANISMS OF DEVELOPMENT / Normal prenatal growth and development. Patterns and mechanisms of growth and maturation. Svoboda - 1 sem. hr.
5V73 ADVANCED HUMAN CRANIOFACIAL DEVELOPMENT AND CRANIOFACIAL ANOMALIES / Detailed investigation of the basic processes and mechanisms of postnatal growth and adaptation of the craniofacial region. This course emphasizes the areas of controversy surrounding the current understanding of the factors influencing postnatal craniofacial growth and form, the adaptive capabilities of growth and form, the adaptive capabilities of craniofacial tissues, the effect of altered function on craniofacial growth and form, and the influence of treatment on craniofacial growth and form. Also considered are theories of craniofacial growth. Svoboda - 1 sem. hr. Variable
5274 SPECIAL PROBLEMS IN POSTNATAL CRANIOFACIAL GROWTH AND DEVELOPMENT / Growth, development, adaptation and aging of craniofacial structures and tissues (especially skeletal); somatic growth and development; clinical implications; theories of craniofacial development. Faculty - 1 sem. hr.
5V75 PHYSICAL GROWTH AND MATURATION / Patterns and mechanisms of postnatal growth and maturation. Buschang - 0.5 sem. hr. Variable
5376 EVOLUTIONARY AND FUNCTIONAL MORPHOLOGY / Comparative anatomy and evolution of craniofacial structure, with emphasis on current techniques of electrophysiology, kinesiology and musculoskeletal biomechanics of orofacial function. Dechow - 1 sem. hr.
5377 BIOLOGY OF BONE AND MINERALIZED TISSUES / Overview of modern studies of bone structure, function and adaptation with specific relevance for the craniofacial region. Faculty - 1 sem. hr.
5278 CARTILAGE BIOLOGY / This course familiarizes the student with the biology of cartilaginous tissues, with emphasis on the structure and metabolism of the chondrocyte and its matrix. Implications for the biomedical properties of the tissue and for the development of degenerative changes are explored. Hinton/Svoboda - 1 sem. hr.
5279 THE TMJ: GROWTH, DEVELOPMENT AND ADAPTATION / Review of the structure and characteristics of the tissues comprising the temporomandibular joint, as well as alterations taking place during prenatal development and postnatal maturation. Current views regarding local environmental determinants of joint adaptation and of the possibilities of growth alteration are presented. Hinton -1 sem. hr.
5V81 SEMINAR: CURRENT ISSUES IN BONE AND MINERALIZED TISSUE BIOLOGY / Topics of current importance in bone and mineralized tissue biology. Dechow - 1 sem. hr.
5190 SEMINAR: CURRENT ISSUES IN SCIENCE / Guest lectures, workshop lectures and discussion; includes topics of current interest to program faculty and students and of general interest in the biomedical sciences. Faculty - 1 sem. hr.
5V91, 5V92 SPECIAL TOPICS IN BIOMEDICAL SCIENCES / Reading and discussion of current literature pertinent to the topic of the seminar. Presentation of papers on selected topics is required for all students. May be used for multiple courses in any one semester. Faculty. Variable
5V93, 5V94, 5V95 DIRECTED READINGS / Individualized courses for single students involved in in-depth study of specific topics in the biomedical sciences. Faculty. Variable
5V96, 5V97 RESEARCH AND SPECIAL PROBLEMS / Concentrated investigation in any area of biomedical sciences. This course is appropriate for individualized laboratory rotations or research. Faculty. Variable
5V98 THESIS RESEARCH AND PREPARATION OF MASTER'S THESIS / Faculty. Variable.
5V99 DISSERTATION / Course used by students after achieving candidacy for research and preparation of Ph.D. dissertation. Faculty. Variable.
Relevant Courses Available at Other Institutions in the Metroplex*
BMS5630 Classical and Molecular Genetics (UTD*)
BMS5631 Eukaryotic Molecular and Cell Biology (UTD)
BMS5632 Biochemistry/Proteins and Nucleic Acids (UTD)
BMS 5633 Molecular Biology (UTD)
BMS5634 Cell Biology (UTD)
BMS 5V35 Methods in Molecular and Cell Biology (UTD)
BMS 5V36 Topics in Molecular Biology (UTD)
CMB5096 Cellular and Molecular Biology (UTSW**)
AE1312 Statistics (UTA***)
AE2312 Dynamics (UTA)
ME2312 Structural Statistics (UTA)
ME5340 Finite Element Application (UTA)
* University of Texas, Dallas; ** University of Texas Southwestern Medical Center; *** University of Texas, Arlington
Courses in Clinical Research Methodology are also offered through UTSW.